01669nas a2200181 4500000000100000008004100001653003900042653001500081653001400096100001600110700001500126700001600141245008200157856007300239300001200312490000600324520115700330 2016 d10aNeglected tropical diseases (NTDs)10aZika virus10aAwareness1 aZammarchi L1 aSpinicci M1 aBartoloni A00aZika virus: a review from the virus basics to proposed management strategies. uhttp://mjhid.pagepress.org/index.php/mjhid/article/view/2016.056/pdf a20160560 v83 a

This review aims to summarize the body of knowledge available on Zika virus to date. A comprehensive review of the scientific literature on Zika virus was performed with the aim to stress relevant aspects for healthcare professionals in non-endemic area. For several years, the Zika virus infection was considered an extremely rare exotic disease with poor clinical relevance. However, Zika virus has recently gained the attention of the scientific community and public opinion since the virus spread to the Pacific islands and the South America in an unprecedented epidemic, and additionally due to the definitive evidence that the infection could be complicated by Guillain-BarrĂ© syndrome, passed through vertical transmission, and result in central nervous system abnormalities (including microcephaly) of the fetus. Studies and scientific evidences on the complications associated with Zika virus infection are growing day by day. It is advisable that the healthcare professionals working in non-endemic areas maintain full awareness on this issue in order to practice proper management of the imported cases of Zika virus infection.