02229nas a2200193 4500000000100000008004100001653001400042653003200056653002200088653001500110100001500125700002700140700001200167245008000179856008800259300001300347490000700360520166800367 2016 d10aSolutions10aNeglected Tropical Diseases10aClinical research10achallenges1 aBoelaert M1 aThe NIDIAG Consortium 1 aAksoy S00aClinical research on neglected tropical diseases: challenges and solutions. uhttp://journals.plos.org/plosntds/article/asset?id=10.1371/journal.pntd.0004853.PDF ae00048530 v103 a

Research pertaining to the neglected tropical diseases (NTDs) poses specific challenges that are linked to the diseases investigated, infrastructure (or lack thereof), culture, social-ecological systems, conflicting health policies, and ethics requirements, among others [13]. In 2010, the European research network on better diagnosis for neglected infectious diseases (NIDIAG consortium; see: http://www.nidiag.org) was launched to carry out collaborative research with an emphasis on NTDs. NIDIAG’s overarching goal was to generate evidence about the spectrum of causal pathogens of selected syndromes in different epidemiologic settings in order to improve the diagnosis and management.

The NIDIAG consortium is composed of research groups from African and Asian countries endemic for human African trypanosomiasis, schistosomiasis, soil-transmitted helminthiasis, visceral leishmaniasis (VL), and other NTDs, together with European biomedical and clinical researchers working on the same topics. The research is facilitated by a grant from the European Union (EU) within the Seventh Framework Programme (FP7). The consortium launched its work on November 1, 2010, for an initial five-year period and an additional six-month no-cost extension until April 30, 2016.