02435nas a2200253   4500000000100000008004100001653000900042653003900051653001700090653001800107653001300125653001700138653001100155100002000166700001200186700001300198700001300211700001500224700001500239700001400254245011600268520178300384022001402167       2016                            d10aWASH10aNeglected tropical diseases (NTDs)10aEpidemiology10aCote d'Ivoire10aChildren10aBuruli ulcer10aAfrica1 aN'krumah RT A S1 aKoné B1 aCissé G1 aTanner M1 aUtzinger J1 aPluschke G1 aTiembre I00aCharacteristics and epidemiological profile of Buruli ulcer in the district of Tiassalé, south Côte d'Ivoire.3 a<p>Buruli ulcer (BU) is a cutaneous infectious disease caused by Mycobacterium ulcerans. It is the third most common mycobacterial disease in the world in the immunocompetent patient and second in Côte d'Ivoire after tuberculosis. This study aimed to assess the characteristics and epidemiological profile of BU in the district of Tiassalé, an important focus of the disease in south Côte d'Ivoire, in order to better direct actions for prevention and control. Retrospective clinical data of BU cases in the period 2005-2010 from all 19 district health centres were collected and linked with geographical and environmental survey data. A total of 1145 cases of BU were recorded between 2005 and 2010 in the district of Tiassalé. Children under the age of 15 years were the most affected (53.0%) with a higher prevalence among males compared to females (54.7% versus 45.3%). Among individuals aged 15-49 years, females had a higher prevalence than males (54.2% versus 45.8%). The villages of Ahondo, Léléblé and Taabo, located in close proximity to the man-made Lake Taabo that was constructed in the late 1970s by damming the Bandama River, and the village of Sokrogbo located downstream of the dam, showed the highest BU rates in the sub-prefecture of Taabo. In the sub-prefecture of Tiassalé, the villages of Affikro, Morokro and N'Zianouan, located near N'Zi River, a tributary of the Bandama River, were the most affected. The distribution of BU is associated with environmental patterns (i.e. distance between village and Lake Taabo or Bandama River and its tributary N'Zi River). Awareness campaigns, coupled with early diagnosis and improved clinical management of BU, have been implemented in the district of Tiassalé and the incidence of BU has declined.</p>
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