01407nas a2200241   4500000000100000008004100001653001500042653001900057653001800076653000900094653001900103653001100122653001500133100003600148700002000184700002500204700002400229700001500253245008900268300001000357520078400367022001401151       2017                            d10aZika virus10aRisk reduction10aPublic health10aNTDs10aKnowledge gaps10aBrazil10aBiothreats1 aGarcia Serpa Osorio-de-Castro C1 aSilva Miranda E1 aMachado de Freitas C1 aRochel de Camargo K1 aCranmer HH00aThe Zika Virus Outbreak in Brazil: Knowledge Gaps and Challenges for Risk Reduction.  ae1-e63 a<p>We analyzed uncertainties and complexities of the Zika virus outbreak in Brazil, and we discuss risk reduction for future emergencies. We present the public health situation in Brazil and concurrent determinants of the epidemic and the knowledge gaps that persist despite building evidence from research, making public health decisions difficult. Brazil has adopted active measures, but producing desired outcomes may be uncertain because of partial or unavailable information. Reducing population group vulnerabilities and acting on environmental issues are medium- to long-term measures. Simultaneously dealing with information gaps, uncontrolled disease spread, and vulnerabilities is a new risk scenario and must be approached decisively to face emerging biothreats.</p>
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