02200nas a2200277 4500000000100000008004100001653003900042653002000081653001000101653002000111653002000131653001100151100001800162700001400180700001800194700001600212700001200228700001200240700001700252245009900269856007000368300001200438490000800450520145000458022001401908 2019 d10aNeglected tropical diseases (NTDs)10aschistosomiasis10aCosts10aCost of Illness10aeconomic burden10aBrazil1 aNascimento GL1 aPegado HM1 aDomingues ALC1 aXimenes RAA1 aItria A1 aCruz LN1 aOliveira MRF00aThe cost of a disease targeted for elimination in Brazil: the case of schistosomiasis mansoni. uhttp://www.scielo.br/pdf/mioc/v114/1678-8060-mioc-114-e180347.pdf ae1803470 v1143 a

BACKGROUND: Schistosomiasis mansoni is a poverty-related parasitic infection that has a variety of clinical manifestations. We consider the disability and deaths caused by schistosomiasis unacceptable for a tool-ready disease. Its condition in Brazil warrants an analysis that will enable better understanding of the local health losses and contribute to the complex decision-making process.

OBJECTIVE: This study estimates the cost of schistosomiasis in Brazil in 2015.

METHODS: We conducted a cost of illness study of schistosomiasis mansoni in Brazil in 2015 based on a prevalence approach and from a societal perspective. The study included 26,499 schistosomiasis carriers, 397 hepatosplenic cases, 48 cases with the neurological form, 284 hospitalisations, and 11,368.26 years of life lost (YLL) of which 5,187 years are attributable to economically active age groups.

RESULTS: The total cost of schistosomiasis mansoni in Brazil was estimated to be US$ 41,7million in 2015 with 94.61% of this being indirect costs.

CONCLUSIONS: The economic burden of schistosomiasis mansoni in Brazil is high and results in the loss of productivity. Its persistence in Brazil is a challenge to public health and requires inter-sectorial interventions in areas such as indoor water supply, basic sanitation, and education.

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