01492nas a2200217 4500000000100000008004100001653001100042653002200053653001600075100001500091700001200106700001300118700001300131700001100144245007100155856007900226300001300305490000700318520093500325022001401260 2019 d10aDengue10aSystematic review10aPhilippines1 aAgrupis KA1 aYlade M1 aAldaba J1 aLopez AL1 aDeen J00aTrends in dengue research in the Philippines: A systematic review. uhttps://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0007280 ae00072800 v133 a

Dengue is an important public health problem in the Philippines. We sought to describe the trends in dengue research in the country. We searched four databases and identified published studies on dengue research in the Philippines during the past 60 years. We reviewed 135 eligible studies, of which 33% were descriptive epidemiologic studies or case series, 16% were entomologic or vector control studies, 12% were studies on dengue virology and serologic response, 10% were socio-behavioral and economics studies, 8% were clinical trials, 7% were on burden of disease, 7% were investigations on markers of disease severity, 5% were on dengue diagnostics, and 2% were modeling studies. During the last decade, dengue research in the Philippines has increased and evolved from simple descriptive studies to those with more complex and diverse designs. We identified several key topics where more research would be useful.

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