02033nas a2200277   4500000000100000008004100001260001200042653002000054653001400074653001100088100001200099700001400111700001200125700001300137700001400150700001600164700001600180700001400196700001700210700001100227245009800238300001100336490000700347520138700354022001401741       2019                            d  c12/201910aschistosomiasis10aMigration10aIsrael1 aParan Y1 aBen-Ami R1 aOrlev B1 aHalutz O1 aElalouf O1 aWasserman A1 aZimmerman O1 aNahmani I1 aRabinowich L1 aFinn T00aChronic schistosomiasis in African immigrants in Israel: Lessons for the non-endemic setting.  ae184810 v983 a<p>To study the clinical presentation of Chronic Schistosomiasis (CS) in immigrants from East Africa to Israel and the tests that were useful in confirming the diagnosis.A retrospective study of all medical notes pertaining to hospitalized patients who were immigrants from East Africa with a pathological or microscopic confirmation of CS. Literature review was also conducted focusing on diagnosis of schistosomiasis among immigrants from endemic countries.We identified 32 suspected and 11 confirmed cases of CS. Most of the patients (82%) presented with gastrointestinal symptoms. Sensitivity of stool smear, serology and tissue diagnosis (by histopathology or microscopy) were 14%, 100%, 89%, respectively. Patients have undergone extensive diagnostic evaluation with long hospitalization stays (median 10 days, range 4 to 33 days).CS has multiple presentations and is seen in Israel among refugees from Eritrea and Sudan. Most of the manifestations are gastrointestinal, suggestive of infection with Schistosoma mansoni (S. mansoni). Standard diagnostic techniques used in endemic countries, such as microscopy for ova and parasites were unhelpful, necessitating more advanced procedures like colonoscopic or liver biopsy. We propose a diagnostic algorithm for CS in this patient population in order to make an accurate diagnosis and avoid unnecessary invasive procedures.</p>  a1536-5964