01497nas a2200169   4500000000100000008004100001653002200042653002100064653002200085100001400107700001700121245014000138856026000278490000700538024001200545520077000557       2020                            d10aClinical research10aGlobal bioethics10aVulnerable groups1 aPentone A1 aFortwengel G00aSocio-cultural and ethical aspects of clinical research in developed and developing countries: different terms for different conditions  uhttps://www.researchgate.net/profile/Gerhard_Fortwengel/publication/338738593_Socio-cultural_and_ethical_aspects_of_clinical_research_in_developed_and_developing_countries_different_terms_for_different_conditions/links/5e27d57b4585150ee7785a25/Socio-cultu0 v11  a10003443 aThis article presents an in-depth analysis of the main socio-cultural and ethical aspects of clinical trials in the “socalled” developed and developing countries as well, through a review of the literature, in order to outline the real background where these kind of research studies are taking place, following the general trend of globalization. The differences between these “two worlds” and the reasons on which they are grounded will highlight the importance of a collaborative research and a global harmonization of effective guidelines and rules with ethical principles, placing clinical trials ’ participants’ rights, safety and well-being over the interests of science and society, with due respect to their community’s culture and tradition.