01855nas a2200217   4500000000100000008004100001260001200042653002000054653001000074100001300084700001500097700001300112700001600125700001300141700001100154700001300165245014100178856016200319520114200481022001401623       2020                            d  c05/202010aschistosomiasis10aSCORE1 aBinder S1 aCampbell C1 aAndros T1 aCastleman J1 aKittur N1 aKing C1 aColley D00aThe Schistosomiasis Consortium for Operational Research and Evaluation 2008-2020: Approaches, Experiences, Lessons, and Recommendations.  uhttp://www.ajtmh.org/docserver/fulltext/10.4269/ajtmh.19-0786/tpmd190786.pdf?expires=1589979438&id=id&accname=guest&checksum=F7B6E0C4C17D363F9F5A9D87FAEA437D3 a<p>For the past 10 years, the Schistosomiasis Consortium for Operational Research and Evaluation (SCORE), funded by the Bill & Melinda Gates Foundation, has been supporting operational research to provide a stronger evidence base for controlling and moving toward elimination of schistosomiasis. The SCORE portfolio was developed and implemented with engagement from many stakeholders and sectors. Particular efforts were made to include endemic country neglected tropical disease program managers. Examples of the challenges we encountered include the need to balance rigor (e.g., conducting large cluster-randomized trials) with ensuring relevance to real-world settings, allowing for local contexts while standardizing key study aspects, adjusting to evolving technologies, and incorporating changing technologies into multiyear studies. The Schistosomiasis Consortium for Operational Research and Evaluation's findings and data and the collected specimens will continue to be useful in the years to come. Our experiences and lessons learned can benefit both program managers and researchers conducting similar work in the future.</p>  a1476-1645