02201nas a2200805   4500000000100000008004100001260000800042653002300050100001400073700001200087700002000099700001500119700001100134700001200145700001400157700001600171700001300187700001100200700001400211700001400225700001500239700001400254700001600268700001300284700001700297700001300314700001200327700001900339700001600358700001300374700001500387700001400402700001600416700001500432700001200447700001400459700001300473700001200486700001800498700001500516700001600531700001300547700001300560700001100573700001200584700001400596700001600610700001700626700001500643700001200658700001300670700001500683700001200698700002000710700001400730700001200744700001300756700001600769700001700785700001300802700001200815700001200827700001400839700001200853245007900865856005900944300001001003520036801013022001401381       2020                            d  bBMJ10aSystematic reviews1 aTugwell P1 aWelch V1 aKarunananthan S1 aMaxwell LJ1 aAkl EA1 aAvey MT1 aBhutta ZA1 aBrouwers MC1 aClark JP1 aCook S1 aCuervo LG1 aCurran JA1 aGhogomu ET1 aGraham IG1 aGrimshaw JM1 aHutton B1 aIoannidis JP1 aJordan Z1 aJull JE1 aKristjansson E1 aLanglois EV1 aLittle J1 aLyddiatt A1 aMartin JE1 aMarušić A1 aMbuagbaw L1 aMoher D1 aMorton RL1 aNasser M1 aPage MJ1 aPardo Pardo J1 aPetkovic J1 aPetticrew M1 aPigott T1 aPottie K1 aRada G1 aRader T1 aRiddle AY1 aRothstein H1 aSchüneman H1 aShamseer L1 aShea BJ1 aSimeon R1 aSiontis KC1 aSmith M1 aSoares-Weiser K1 aThavorn K1 aTovey D1 aVachon B1 aValentine J1 aVillemaire R1 aWalker P1 aWeeks L1 aWells G1 aWilson DB1 aWhite H00aWhen to replicate systematic reviews of interventions: consensus checklist  uhttps://www.bmj.com/content/bmj/370/bmj.m2864.full.pdf  am28643 aReplication is an essential part of the scientific method, yet replication of systematic reviews is too often overlooked, and done unnecessarily or poorly. Excessive replication (doing the same study repeatedly) is unethical and a cause of research wastage. This article provides consensus based guidance on when to replicate and not replicate systematic reviews.  a1756-1833