01349nas a2200205 4500000000100000008004100001260003700042653005700079653002400136100001500160700001600175700001300191700001600204245007700220856009900297300001300396490000700409520071300416022001401129 2020 d bPublic Library of Science (PLoS)10aPublic Health, Environmental and Occupational Health10aInfectious Diseases1 aYoshioka K1 aHashimoto K1 aMonroy C1 aDebrabant A00aHas the prevalence of Chagas disease increased in Central Latin America? uhttps://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0008851&type=printable ae00088510 v143 aIn their editorial published in PLOS NTDs, Hotez et al. [1] wrote that “the GBD 2017 [Global Burden of Disease Study 2017] tells a sobering story about progress in controlling malaria and NTDs [neglected tropical diseases]” in Central Latin America (CLA). CLA is a region defined by the GBD 2017, including Mexico, Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica, Panama, Colombia and Venezuela. As part of the sobering story, Hotez et al. [1] found that the prevalence of Chagas disease increased by 16% from 2000 to 2017, implying that its control has not progressed during the last two decades. In this article, we show that the GBD 2017 can tell a different story about Chagas disease in CLA. a1935-2735