01530nas a2200229   4500000000100000008004100001260003200042653002100074653001300095100001900108700001400127700002000141700001400161700002400175700002000199700001300219245015100232856007200383490000700455520082400462022001401286       2020                            d  bPan African Medical Journal10aGeneral Medicine10aCovid-191 aTcheutchoua DN1 aTankeu AT1 aWouna Angong DL1 aAgoons BB1 aYanwou Nguemnang NY1 aNana Djeunga HC1 aKamgno J00aUnexpected low burden of coronavirus disease 2019 (COVID-19) in sub-Saharan Africa region despite disastrous predictions: reasons and perspectives  uhttps://www.panafrican-med-journal.com/content/article/37/352/full/0 v373 aThe severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the development of a highly contagious disease called coronavirus disease (COVID-19). Ten months after the onset of the pandemic, America and Europe remain the most affected regions. Initially, experts predicted that Africa, the poorest continent with the most vulnerable population and health system, would be greatly affected by the ongoing outbreak. However, 240days after the first confirmed case, Africa is among the least affected region, with lower than expected incident cases and mortality. In this review, we discuss possible explanations and reasons for this unexpected low burden of COVID-19 in Africa. We focus on the characteristics of the virus, specificities of the sub-Saharan African population and local environment.  a1937-8688