02236nas a2200241 4500000000100000008004100001260004400042653005700086653002100143100001400164700001200178700001200190700001300202700001700215700001600232700001600248700001200264245011000276856007300386490000700459520151400466022001401980 2021 d bSpringer Science and Business Media LLC10aGeneral Biochemistry, Genetics and Molecular Biology10aGeneral Medicine1 aKwizera R1 aMande E1 aOmali D1 aOkurut S1 aNabweyambo S1 aNabatanzi R1 aNakanjako D1 aMeya DB00aTranslational research in Uganda: linking basic science to bedside medicine in a resource limited setting uhttps://link.springer.com/content/pdf/10.1186/s12967-021-02747-z.pdf0 v193 aAbstract Background Translational research is a process of applying knowledge from basic biology and clinical trials to techniques and tools that address critical medical needs. Translational research is less explored in the Ugandan health system, yet, it is fundamental in enhancing human health and well-being. With the current high disease burden in Uganda, there are many opportunities for exploring, developing and utilising translational research. Main body In this article, we described the current state, barriers and opportunities for translational research in Uganda. We noted that translational research is underutilised and hindered by limited funding, collaborations, laboratory infrastructure, trained personnel, equipment and research diversity. However, with active collaborations and funding, it is possible to set up and develop thriving translational research in Uganda. Researchers need to leverage existing international collaborations to enhance translational research capacity development. Conclusion Expanding the integration of clinical and translational research in Uganda health care system will improve clinical care.  a1479-5876