02283nas a2200205 4500000000100000008004100001260002300042653001200065100001500077700001500092700002200107700001100129700002000140700001100160245011000171856008600281300000800367520167700375022002502052 2021 d bInforma UK Limited 10 aSurgery 1 aCalonge WM 1 aMeredith P 1 aKouakou-Adonis KA 1 aYao CK 1 aN’da Assie KM 1 aAsse H 00 aReconstructive surgery for sequellae of Mycobacterium ulcerans infection (Buruli ulcer) of the upper limb uhttps://www.tandfonline.com/doi/pdf/10.1080/2000656X.2021.1884083?needAccess=true a1-6 3 aIntroduction
Infection by Mycobacterium ulcerans constitutes a neglected tropical disease whose prevalence seems to have overrun those of cutaneous tuberculosis and leprosy. Its aggressivity depends on a mycolactone toxin. Lesions may involve skin, tendon and bone with a large spectrum of manifestations: non-ulcerative (papules, nodules, plaques), ulcerative and oedematous presentations as well as osteomyelitis with muscular contraction and ankylosis. Upper limbs account for more than two thirds of the infection sites. Surgical treatment may involve tendon transpositions, partial and total skin grafts. Amputation is relegated to extreme cases.
Material and methods
Selected iconography from patients during the last 15 years is presented. At least 1500 cases had partial skin grafts (anterior thigh). Total skin grafts (inguinal region) were used in about 200 cases. Complex lesions involved 9 ilioinguinal flaps (5 boys, 4 girls, mean age 11.2 years, range 2–16 years), 5 tendon transfers (4 boys, one girl, mean age 15.4 years, range 12–19 years) and 3 resections of the first carpal row (2 girls, 1 boy, mean age 8 years, range 4–15 years).
Results and discussion
Out of 9 ilioinguinal flaps mild, marginal necrosis was the only complication in 2 patients without flap loss. Mean hospital stay was 26.44 days (range, 18–41 days), with return to full weight-bearing after a mean of 12 weeks (range 9–25 weeks) after discharge. Functional thumb opposition to allow pencil prehension was achieved in all three cases of resection of first carpal row resection without postoperative complications. a2000-656X, 2000-6764