03219nas a2200205 4500000000100000008004100001260004400042653001800086100002100104700001400125700002100139700001200160700001700172700001900189245014100208856008800349490000700437520255500444022001402999 2021 d bSpringer Science and Business Media LLC10aHealth Policy1 aSant Fruchtman C1 aMbuyita S1 aMwanyika-Sando M1 aBraun M1 ade Savigny D1 aCobos Muñoz D00aThe complexity of scaling up an mHealth intervention: the case of SMS for Life in Tanzania from a health systems integration perspective uhttps://bmchealthservres.biomedcentral.com/track/pdf/10.1186/s12913-021-06285-8.pdf0 v213 aAbstract Background SMS for Life was one of the earliest large-scale implementations of mHealth innovations worldwide. Its goal was to increase visibility to antimalarial stock-outs through the use of SMS technology. The objective of this case study was to show the multiple innovations that SMS for Life brought to the Tanzanian public health sector and to discuss the challenges of scaling up that led to its discontinuation from a health systems perspective. Methods A qualitative case-study approach was used. This included a literature review, a document review of 61 project documents, a timeline of key events and the collection and analysis of 28 interviews with key stakeholders involved in or affected by the SMS for Life programme. Data collection was informed by the health system building blocks. We then carried out a thematic analysis using the WHO mHealth Assessment and Planning for Scale (MAPS) Toolkit as a framework. This served to identify the key reasons for the discontinuation of the programme. Results SMS for Life was reliable at scale and raised awareness of stock-outs with real-time monitoring. However, it was discontinued in 2015 after 4 years of a national rollout. The main reasons identified for the discontinuation were the programme’s failure to adapt to the continuous changes in Tanzania’s health system, the focus on stock-outs rather than ensuring appropriate stock management, and that it was perceived as costly by policy-makers. Despite its discontinuation, SMS for Life, together with co-existing technologies, triggered the development of the capacity to accommodate and integrate future technologies in the health system. Conclusion This study shows the importance of engaging appropriate stakeholders from the outset, understanding and designing system-responsive interventions appropriately when scaling up and ensuring value to a broad range of health system actors. These shortcomings are common among digital health solutions and need to be better addressed in future implementations.  a1472-6963