01858nas a2200229 4500000000100000008004100001260001200042100001500054700001400069700001200083700001500095700001400110700001300124700001300137700001200150700002100162700001300183700001500196245009400211856007900305520124400384 2021 d c01/20211 aBlumberg S1 aBorlase A1 aPrada J1 aSolomon AW1 aEmerson P1 aHooper P1 aDeiner M1 aAmoah B1 aHollingsworth DT1 aPorco TC1 aLietman TM00aImplications of the COVID-19 pandemic on eliminating trachoma as a public health problem. uhttps://academic.oup.com/trstmh/article-pdf/115/3/222/36508504/traa170.pdf3 a
Background: Progress towards elimination of trachoma as a public health problem has been substantial, but the COVID-19 pandemic has disrupted community-based control efforts.
Methods: We use a susceptible-infected model to estimate the impact of delayed distribution of azithromycin treatment on the prevalence of active trachoma.
Results: We identify three distinct scenarios for geographic districts depending on whether the basic reproduction number and the treatment-associated reproduction number are above or below a value of one. We find that when the basic reproduction number is below one, no significant delays in disease control will be caused. However, when the basic reproduction number is above one, significant delays can occur. In most districts a year of COVID-related delay can be mitigated by a single extra round of mass drug administration. However, supercritical districts require a new paradigm of infection control because the current strategies will not eliminate disease.
Conclusion: If the pandemic can motivate judicious, community-specific implementation of control strategies, global elimination of trachoma as a public health problem could be accelerated.