01755nas a2200265 4500000000100000008004100001260001200042100001300054700001100067700001800078700001200096700001800108700001100126700001500137700002400152700001300176700001400189700001300203700001600216700001200232245005700244300001100301520116300312022001401475 2021 d c05/20211 aLiblik K1 aByun J1 aSaldarriaga C1 aPerez G1 aLopez-Santi R1 aWyss F1 aLiprandi A1 aMartínez-Sellés M1 aFarina J1 aMendoza I1 aBurgos L1 aBaranchuk A1 aHeart N00aSnakebite Envenomation and Heart: Systematic Review. a1008613 a

Snakebite envenomation is a neglected tropical disease which can result in morbidity and mortality. Cardiac implications are poorly understood due to the low frequency of cardiotoxicity combined with a lack of robust information, as snakebites commonly occur in remote and rural areas. This review aims to assess cardiovascular implications of snakebite envenoming and proposes an algorithm for screening of cardiovascular manifestations. A systematic review was performed and 29 articles relating to cardiovascular involvement in snakebite envenomation were selected. Cardiovascular involvement seems to be rare and includes a wide spectrum of outcomes, such as myocardial infarction, ventricular dysfunction, hypotension, cardiac arrest, and myocarditis. In a significant proportion of the cases analyzed (24.39%), the cardiovascular manifestations had major consequences (cardiac arrest, myocardial infarction, malignant ventricular arrhythmias, or death). Clinical monitoring, physical examination, and early electrocardiogram should be considered as key measures to detect cardiovascular involvement in patients with evidence of systemic illness.

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