02168nas a2200205   4500000000100000008004100001260003300042100001500075700001600090700001400106700001700120700001400137700001600151700001500167245009900182856008100281490000700362520157900369022001401948       2021                            d  c06/2021bFapUNIFESP (SciELO)1 aBaldoni NR1 aQuintino ND1 aAlves GCS1 aOliveira CDL1 aSabino EC1 aRibeiro ALP1 aCardoso CS00aQuality of life in patients with Chagas disease and the instrument used: an integrative review  uhttps://www.scielo.br/j/rimtsp/a/fJY3k5KyPNt6rT8Bt5Y45Hx/?format=pdf&lang=en0 v633 aChagas disease (CD) is a neglected tropical highly morbid disease that can have a negative impact on the quality of life (QoL). The purpose of this study was to conduct an integrative review to analyze the QoL of patients with CD in the chronic phase of the disease, as well as the instruments used and the effect of different interventions. The review was carried out based on the criteria and recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes guideline (PRISMA) using the PubMed, Scopus, Web of Science and Science Direct databases. An analysis of the reference list of the included articles was also carried out. Publications in all languages have been included. Two independent reviewers selected the eligible articles and extracted the data. A total of 1,479 articles were identified, and after applying the inclusion criteria 18 articles were included. Four different instruments were used to assess QoL and the most used was the Minnesota Living with Heart Failure Questionnaire (MLWHFQ) [33.3% (n = 6)]. Investigations involving intervention showed a positive impact on the patients’ QoL, and the Environment domain had the lowest score. Heterogeneity of instruments and lack of methodology standardization for assessing QoL was observed. QoL proved to be an important indicator for the planning and monitoring of patients with CD, however it is suggested that the instruments for its assessment should be the ones recommended by the validation studies. This process will allow the comparison of data between investigations.  a1678-9946