02704nas a2200385   4500000000100000008004100001260005400042653001700096653001300113653002400126100001400150700001700164700001500181700001700196700001100213700001300224700001600237700001900253700001400272700001500286700001400301700001400315700001400329700001300343700001500356700001400371700001300385700001400398245013900412856008100551300001400632490000800646520163900654022002502293       2021                            d  bAmerican Society of Tropical Medicine and Hygiene10aParasitology10aVirology10aInfectious Diseases1 aCooley GM1 aFeldstein LR1 aBennett SD1 aEstivariz CF1 aWeil L1 aBohara R1 aVandenent M1 aMainul Hasan A1 aAkhtar MS1 aUzzaman MS1 aBillah MM1 aConklin L1 aEhlman DC1 aAsiedu K1 aSolomon AW1 aAlamgir A1 aFlora MS1 aMartin DL00aNo Serological Evidence of Trachoma or Yaws Among Residents of Registered Camps and Makeshift Settlements in Cox’s Bazar, Bangladesh  uhttps://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC8176462&blobtype=pdf  a2031-20370 v1043 a<jats:title>Abstract.</jats:title><jats:p>Successful achievement of global targets for elimination of trachoma as a public health problem and eradication of yaws will require control efforts to reach marginalized populations, including refugees. Testing for serologic evidence of transmission of trachoma and yaws in residents of registered camps and a Makeshift Settlement in Cox’s Bazar District, Bangladesh, was added to a serosurvey for vaccine-preventable diseases (VPDs) conducted April–May 2018. The survey was primarily designed to estimate remaining immunity gaps for VPDs, including diphtheria, measles, rubella, and polio. Blood specimens from 1- to 14-year-olds from selected households were collected and tested for antibody responses against antigens from <jats:italic>Treponema pallidum</jats:italic> and <jats:italic>Chlamydia trachomatis</jats:italic> using a multiplex bead assay to evaluate for serologic evidence of the neglected tropical diseases (NTDs) yaws and trachoma, respectively. The prevalence of antibodies against two <jats:italic>C. trachomatis</jats:italic> antigens in children ranged from 1.4% to 1.5% for Pgp3 and 2.8% to 7.0% for CT694. The prevalence of antibody responses against both of two treponemal antigens (recombinant protein17 and treponemal membrane protein A) tested was 0% to 0.15% in two camps. The data are suggestive of very low or no transmission of trachoma and yaws, currently or previously, in children resident in these communities. This study illustrates how integrated serologic testing can provide needed data to help NTD programs prioritize limited resources.</jats:p>  a0002-9637, 1476-1645