02470nas a2200397 4500000000100000008004100001260003700042653002400079653005700103100001400160700001400174700001300188700001400201700001300215700001200228700001500240700001500255700001200270700001500282700001200297700001500309700001300324700002500337700001200362700001300374700001800387700001500405700001600420700001900436245017300455856009900628300001300727490000700740520131100747022001402058 2021 d bPublic Library of Science (PLoS)10aInfectious Diseases10aPublic Health, Environmental and Occupational Health1 aJúnior J1 aRamos ACV1 aAlves JD1 aCrispim J1 aAlves LS1 aBerra T1 aBarbosa TP1 aCosta FBPD1 aAlves Y1 aSantos MSD1 aGomes D1 aYamamura M1 aPinto IC1 aFuentealba-Torres MA1 aNunes C1 aPieri FM1 aArcoverde MAM1 aSantos FLD1 aArcêncio R1 aNovaes Ramos A00aInequality of gender, age and disabilities due to leprosy and trends in a hyperendemic metropolis: Evidence from an eleven-year time series study in Central-West Brazil uhttps://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0009941&type=printable ae00099410 v153 a

The present study aimed to investigate the epidemiological situation of leprosy (Hansen’s Disease), in a hyperendemic metropolis in the Central-West region of Brazil. We studied trends over eleven years, both in the detection of the disease and in disabilities, analyzing disparities and/or differences regarding gender and age. This is an ecological time series study conducted in Cuiabá, capital of the state of Mato Grosso. The population consisted of patients diagnosed with leprosy between the years 2008 and 2018. The time series of leprosy cases was used, stratifying it according to gender (male and female), disability grade (G0D, G1D, G2D, and not evaluated) and age. The calendar adjustment technique was applied. For modeling the trends, the Seasonal-Trend decomposition procedure based on Loess (STL) was used. We identified 9.739 diagnosed cases, in which 58.37% were male and 87.55% aged between 15 and 59 years. Regarding detection according to gender, there was a decrease among women and an increase in men. The study shows an increasing trend in disabilities in both genders, which may be related to the delay in diagnosis. There was also an increasing number of cases that were not assessed for disability at the time of diagnosis, which denotes the quality of the services.

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