02356nas a2200253 4500000000100000008004100001260004400042653002400086653001700110653001200127100001400139700001500153700001900168700001200187700001400199700001300213700001500226700001500241245010400256856009100360490000700451520163000458022001402088 2022 d bSpringer Science and Business Media LLC10aInfectious Diseases10aParasitology10aAnaemia1 aBauleni A1 aTiruneh FN1 aMwenyenkulu TE1 aNkoka O1 aChirwa GC1 aGowelo S1 aChipeta MG1 aNtenda PAM00aEffects of deworming medication on anaemia among children aged 6–59 months in sub-Saharan Africa uhttps://parasitesandvectors.biomedcentral.com/track/pdf/10.1186/s13071-021-05123-4.pdf0 v153 a

Abstract Background Despite the limited knowledge regarding the effects of deworming medication (DM) on nutritional indicators in sub-Saharan Africa (SSA), deworming programmes continue to be implemented in resource-limited countries. Therefore, the current study aimed to examine the effects of DM on anaemia among children aged 6–59 months in SSA. Methods The analysis was performed using data obtained from 17 demographic and health surveys (DHSs) conducted in SSA. Children were considered to be anaemic if their haemoglobin (Hb) concentration was less than 11.0 g/dl, adjusting for altitude. To account for both multiple measures at the cluster level and the clustering of children within the same country, generalized linear mixed models were used to analyse the anaemia outcomes in 50,075 children aged 6–59 months. Results Overall, anaemia was reported in 61.8% of the children, and their median Hb concentration was 10.5 g/dl (interquartile range 9.4–11.5). The prevalence of anaemia ranged from 34.5% in Rwanda to 81.1% in Mali. Multivariate analyses showed that children who did not receive DM had increased odds of being anaemic (adjusted odds ratio [aOR]: 1.11; 95% confidence interval [CI] 1.07–1.16). Conclusions The current study revealed that DM can decrease the risk of anaemia among preschool-age children (pre-SAC) in SSA. Thus, tailored public health programmes aimed at reducing childhood anaemia need to consider deworming. However, longitudinal studies are needed to validate the association that has been reported in this cross-sectional study. Graphical Abstract

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