02112nas a2200253 4500000000100000008004100001260001600042653002400058653001700082653001700099100001500116700001300131700001100144700001400155700001700169700001300186700001200199245012900211856015300340300001100493490000700504520133300511022001401844 2022 d bElsevier BV10aInfectious Diseases10aParasitology10aEpidemiology1 aKarmaoui A1 aSereno D1 aMaia C1 aCampino L1 aEl Jaafari S1 aTaybi AF1 aHajji L00aA conceptual model for understanding the zoonotic cutaneous leishmaniasis transmission risk in the Moroccan pre-Saharan area uhttps://www.sciencedirect.com/science/article/pii/S2405673122000071/pdfft?md5=0a1382809c3b2d7bfee5a63cb46ee640&pid=1-s2.0-S2405673122000071-main.pdf ae002430 v173 a

Leishmanioses are of public health concern in Morocco, mainly the Zoonotic Cutaneous Leishmaniasis (ZCL) endemic in the Moroccan pre-Saharian area. Transmission of this disease depends on eco-epidemiological and socio-economic conditions. Therefore, a multivariable approach is required to delineate the risk and intensity of transmission. This will help outline main disease risk factors and understand interactions between all underlying factors acting on disease transmission at a local and regional scale. In this context, we propose a new conceptual model, the Biophysical-Drivers-Response-Zoonotic Cutaneous Leishmaniasis (BDRZCL), adapted to the Pre-Saharian area. The proposed model highlights how the physical and human drivers affect the environment and human health. The incidence of ZCL is linked to human activity and biophysical changes or by their interactions. The human response added to risk drivers are the main components that influence the biophysical part. This model improves our understanding of the cause-effect interactions and helps decision-makers and stakeholders react appropriately.

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