02039nas a2200193 4500000000100000008004100001260003400042653005700076653002100133100001300154700001200167700001200179700001300191700001600204245008500220856010800305520140700413022002501820 2022 d bOxford University Press (OUP)10aPublic Health, Environmental and Occupational Health10aGeneral Medicine1 aYoong SL1 aTuron H1 aGrady A1 aHodder R1 aWolfenden L00aThe benefits of data sharing and ensuring open sources of systematic review data uhttps://academic.oup.com/jpubhealth/advance-article-pdf/doi/10.1093/pubmed/fdac031/42893012/fdac031.pdf3 a

Aims The benefits of increasing public access to data from clinical trials are widely accepted. Such benefits extend to the sharing of data from high-quality systematic reviews, given the time and cost involved with undertaking reviews. We describe the application of open sources of review data, outline potential challenges and highlight efforts made to address these challenges, with the intent of encouraging publishers, funders and authors to consider sharing review data more broadly.

Results We describe the application of systematic review data in: (i) advancing understanding of clinical trials and systematic review methods, (ii) repurposing of data to answer public health policy and practice relevant questions, (iii) identification of research gaps and (iv) accelerating the conduct of rapid reviews to inform decision making. While access, logistical, motivational and legal challenges exist, there has been progress made by systematic review, academic and funding agencies to incentivise data sharing and create infrastructure to support greater access to systematic review data.

Conclusion There is opportunity to maximize the benefits of research investment in undertaking systematic reviews by ensuring open sources of systematic review data. Efforts to create such systems should draw on learnings and principles outlined for sharing clinical trial data.

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