03175nas a2200397   4500000000100000008004100001260003700042653002400079653005700103653001200160100001400172700001700186700001900203700001500222700001900237700001600256700001700272700001700289700001700306700001600323700001300339700001400352700001600366700001200382700001200394700001400406700001400420700001400434700001300448245014200461856009900603300001300702490000700715520204100722022001402763       2022                            d  bPublic Library of Science (PLoS)10aInfectious Diseases10aPublic Health, Environmental and Occupational Health10aAnaemia1 aJohari NA1 aAnnuzaili DA1 aEl-Talabawy HF1 aBa-Break M1 aAl-Mekhlafi AM1 aAl-Eryani S1 aAlkohlani AA1 aGabrielli AF1 aBen-Ismail R1 aAlhaidari S1 aMuaydh A1 aAlshami R1 aAL Gunaid M1 aHamed A1 aKamel N1 aPalacio K1 aFleming F1 aFrench MD1 aRamos AN00aNational mapping of schistosomiasis, soil-transmitted helminthiasis and anaemia in Yemen: Towards better national control and elimination  uhttps://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0010092&type=printable  ae00100920 v163 a<p>Background</p>

<p>Schistosomiasis (SCH) and soil-transmitted helminthiasis (STH) are known to be endemic in Yemen. However, the distribution of both diseases had not previously been assessed by a well-structured national mapping study covering all governorates. The main aim of this study was, therefore, to map the prevalence of SCH and STH in Yemen in order to better inform implementation of effective national control and elimination interventions. The assessment of the distribution of anaemia was also included as a well-known consequence of infection with both SCH and STH. Secondarily, the study aimed to provide a broad indication of the impact of large-scale treatment on the distribution of infection.</p>

<p>Methodology and principal findings</p>

<p>To achive these aims, 80,432 children (10–14 years old) from 2,664 schools in 332 of Yemen’s 333 districts were included, in 2014, into this national cross-sectional survey. Countrywide, 63.3% (210/332) and 75.6% (251/332) of districts were found to be endemic for SCH and STH respectively. More districts were affected by intestinal than urogenital SCH (54.2% and 31.6% respectively). SCH infection was mostly mild and moderate, with no districts reporting high infection. One quarter (24.4%) of Yemeni districts had high or moderate levels of Ascaris lumbricoides infection. Infection with Trichuris trichiura was the second most common STH (44.9% of districts infected) after A. lumbricoides (68.1%). Hookworm was the least prevalent STH (9.0%). Anaemia was prevalent in 96.4% of districts; it represented a severe public health problem (prevalence ≥ 40%) in 26.5% of districts, and a mild to moderate problem in two thirds of the districts (33.7% and 36.1% respectively).</p>

<p>Conclusion</p>

<p>This study provided the first comprehensive mapping of SCH, STH, and anaemia across the country. This formed the basis for evaluating and continuing the national control and elimination programme for these neglected tropical diseases in Yemen.</p>
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