01502nas a2200205   4500000000100000008004100001260001600042653002400058653001700082100001400099700001400113700001400127700001200141700001600153700001600169245007700185856015300262520086700415022001401282       2022                            d  bElsevier BV10aInfectious Diseases10aParasitology1 aTirados I1 aThomsen E1 aWorrall E1 aKoala L1 aMelachio TT1 aBasáñez M00aVector control and entomological capacity for onchocerciasis elimination  uhttps://www.sciencedirect.com/science/article/pii/S1471492222000605/pdfft?md5=bb2d02a3b73136c308f1ff70b8c6d03f&pid=1-s2.0-S1471492222000605-main.pdf3 a<p>Mass drug administration (MDA) of ivermectin is currently the main strategy to achieve elimination of transmission (EoT) of onchocerciasis. Modelling suggests that EoT may not be reached in all endemic foci using annual MDA alone. Onchocerciasis and loiasis are coendemic in forest areas of Central Africa where ivermectin treatment can lead to severe adverse events in individuals with heavy loiasis load, rendering MDA inappropriate. Vector control has been proposed as a complementary intervention strategy. Here, we discuss (i) achievements and pitfalls of previous interventions; (ii) epidemiological impact, feasibility, and combination with MDA to accelerate and/or protect EoT; (iii) role of modelling; (iv) opportunities for innovative methods of vector monitoring and control; and (v) strengthening entomological capacity in endemic countries.</p>
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