01937nas a2200205 4500000000100000008004100001260002300042653002800065653004000093100001300133700001300146700001300159700001100172700001200183700001500195245014400210300000900354520134300363022002501706 2022 d bInforma UK Limited10aEarth-Surface Processes10aGeography, Planning and Development1 aLukou YS1 aAtari DO1 aSube KLL1 aLako J1 aOchi EB1 aElrayah IE00aThe risk and associated control problems of Human African Trypanosomosis (HAT) in the endemic foci of Greater Equatoria Region, South Sudan a1-163 a

This study aims to analyze, map, and identify the prevalence of, service provision for, and risk distribution and control for Human African Trypanosomosis (HAT), or sleeping sickness, in the endemic areas of Greater Equatoria Region (GER), including Eastern, Central, and Western Equatoria States of South Sudan. Passive and active screening data, detection data, and existing facilities and centers for sleeping sickness were used to assess the prevalence, screening coverage, and overall risk in the region for the 2016–2018 period. In addition, historical literature and surveillance information were used. The results show that 0.43% (N = 14,552) of the total at-risk population (N = 3,399,400) of GER were subjected to passive or active screening for Gambian HAT (gHAT), which showed an infection rate of 0.30%. Out of the total area of 196,211 km2, 58.77% of the region (115,311 km2) was found to be endemic to HAT. The population remains at high or very high risk for the disease in Western Equatoria State due to a number of active historic gHAT foci. With relative peace currently prevailing in the region, there is need to reinforce the leadership of South Sudan’s health ministry with sufficient internal and external resources to support its activities.

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