02028nas a2200277   4500000000100000008004100001260001200042653002400054653005700078653004000135100001400175700001600189700001700205700001700222700001800239700001700257700002500274700001700299700001300316245011300329856006600442300000800508490000600516520121400522022001401736       2021                            d  bMDPI AG10aInfectious Diseases10aPublic Health, Environmental and Occupational Health10aGeneral Immunology and Microbiology1 aSilva BMD1 aFerreira AF1 ada Silva JAM1 ade Amorim RG1 aDomingues ALC1 aPinheiro MCC1 ade Moraes Bezerra FS1 aHeukelbach J1 aRamos AN00aPersistence of Schistosomiasis-Related Morbidity in Northeast Brazil: An Integrated Spatio-Temporal Analysis  uhttps://www.mdpi.com/2414-6366/6/4/193/pdf?version=1635920035  a1930 v63 a<p>Objective: To analyze the temporal trend and spatial patterns of schistosomiasis-related morbidity in Northeast Brazil, 2001–2017. Methods: Ecological study, of time series and spatial analysis, based on case notifications and hospital admission data, as provided by the Ministry of Health. Results: Of a total of 15,574,392 parasitological stool examinations, 941,961 (6.0%) were positive, mainly on the coastline of Pernambuco, Alagoas and Sergipe states. There was a reduction from 7.4% (2002) to 3.9% (2017) of positive samples and in the temporal trend of the detection rate (APC—11.6*; Confidence Interval 95%—13.9 to −9.1). There was a total of 5879 hospital admissions, with 40.4% in Pernambuco state. The hospitalization rate reduced from 0.82 (2001) to 0.02 (2017) per 100,000 inhabitants. Conclusion: Despite the reduction in case detection and hospitalizations, the persistence of focal areas of the disease in coastal areas is recognized. This reduction may indicate a possible positive impact of control on epidemiological patterns, but also operational issues related to access to healthcare and the development of surveillance and control actions in the Unified Health System.</p>
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