01686nas a2200157   4500000000100000008004100001100001000042700001500052700001400067700001500081700001500096245019400111856020000305490000700505520101600512       2022                            d1 aOjo R1 aAdekanye I1 aOdedele T1 aOladokun O1 aAkindele Z00aNeglected Tropical Disease as an Hidden Cause of Cardiovascular Diseases: A Systematic Review of Cardiovascular Manifestations of Schistosomiasis, African Trypanosomiasis and Chagas Disease  uhttps://www.longdom.org/pdfdownload.php?download=open-access/neglected-tropical-disease-as-an-hidden-cause-of-cardiovascular-diseases-a-systematic-review-of-cardiovascular-manifesta.pdf&aid=920780 v133 a<p>Neglected tropical diseases as been disease conditions that affect people particularly those living in the Tropical regions of the world, these disease entities affects many system of the body which therefore added to the burden of these disease. Some of these diseases affect the heart, blood vessels and other part of the cardiovascular system some presenting as life threatening conditions. Among these neglected tropical diseases that affect the cardiovascular system are schistosomiasis, African trypanosomiasis and Chagas disease which are the focus of this study. Schistosomiasis and African trypanosomiasis have been finding to be endemic in Africa while Chagas disease is found to be endemic in rural Americas communities. Some of these diseases especially schistosomiasis affects the heart causing the cardiomyocytes to fibros a condition called endomyocardial fibrosis while others causes some ischemic and inflammatory changes to the heart and other components of the cardiovascular system.</p>