02379nas a2200217   4500000000100000008004100001260001000042653001600052653001200068100001200080700001200092700002200104700001200126700001500138245016100153856026000314300001200574490000700586520155400593022001402147       2014                            d  bWiley10aDermatology10aSurgery1 aBlome C1 aBaade K1 aSebastian Debus E1 aPrice P1 aAugustin M00aThe “Wound-QoL”: A short questionnaire measuring quality of life in patients with chronic wounds based on three established disease-specific instruments  uhttps://www.researchgate.net/profile/Christine-Blome/publication/262882967_The_'Wound-QoL'_A_Short_Questionnaire_Measuring_Quality_of_Life_in_Patients_with_Chronic_Wounds_Based_on_Three_Established_Disease-specific_Instruments/links/56c33f0b08ae8a6fab59f8  a504-5140 v223 a<p>Aim of this study was to develop a short questionnaire measuring health-related quality of life (HRQoL) in chronic wounds. Three validated instruments assessing HRQoL in chronic wounds, the Freiburg Life Quality Assessment for wounds, the Cardiff Wound Impact Schedule, and the Würzburg Wound Score, were completed by 154 German leg ulcer patients in a longitudinal study. For implementation in the new, shorter questionnaire Wound-QoL, those of all 92 items were selected that covered the core content of the three questionnaires and showed good psychometric properties. Internal consistency, convergent validity, and responsiveness were analysed using the study data on the selected items (a new approach called virtual validation). Subscales were determined with factor analysis. Item, instruction, and response scale wording were harmonized. 17 items were included in the Wound-QoL which could be attributed to three subscales on everyday life, body, and psyche. Both global score and subscale scores were internally consistent with Cronbach's alpha between 0.71 and 0.91. The global score showed significant convergent validity (r = 0.48 to 0.69) and responsiveness (r = 0.18 to 0.52); the same was true for the subscale scores. The Wound-QoL for measurement of HRQoL in chronic wounds proved to be internally consistent, valid, and responsive in German leg ulcer patients. The findings of this virtual validation study need to be confirmed in a longitudinal validation study on the final Wound-QoL which is currently being conducted.</p>
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