01972nas a2200265 4500000000100000008004100001260001200042653003900054653005700093100002000150700001200170700001500182700001400197700001200211700001300223700001500236700001400251700001300265245011000278856007000388300001000458490000700468520121700475022001401692 2022 d bMDPI AG10aHealth, Toxicology and Mutagenesis10aPublic Health, Environmental and Occupational Health1 aAbdul Halim AFN1 aAhmad D1 aMiaw Yn JL1 aMasdor NA1 aRamly N1 aOthman R1 aKandayah T1 aHassan MR1 aDapari R00aFactors Associated with the Acceptability of Mass Drug Administration for Filariasis: A Systematic Review uhttps://www.mdpi.com/1660-4601/19/19/12971/pdf?version=1665406054 a129710 v193 a

Mass drug administration (MDA) has been implemented as a tool to eliminate lymphatic filariasis. Acceptability among susceptible populations is crucial to achieving MDA effective coverage. This systematic review aims to present and systematically determine the factors associated with the acceptability of MDA. Articles related to factors associated with acceptability were collected electronically from three different databases (Scopus, Web of Science, and PubMed). Four pairs of independent reviewers screened the titles and abstracts of the collected data, stored in EndnoteX7, against the inclusion criteria. Afterwards, the included articles have been critically appraised to assess the quality of the studies using the Mixed Method Appraisal Tool (MMAT). Of the 68 articles identified, 11 were included in the final review. Knowledge, awareness, attitude and perceptions, communications, delivery and accessibility of MDA, gender, and age are the factors associated with MDA acceptability. Community acceptance remains a challenge in the implementation of MDA. To expand MDA coverage in all endemic countries, there is a strong need to address the factors influencing community acceptance of MDA.

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