01815nas a2200145   4500000000100000008004100001260001600042100001100058700000900069700001600078245007700094856015300171520133100324022001401655       2023                            d  bElsevier BV1 aChen J1 aHe J1 aBergquist R00aChallenges and response to pandemics as seen in a One Health perspective  uhttps://www.sciencedirect.com/science/article/pii/S2949704323000045/pdfft?md5=70b711942816156b0a4ace1cde0d60f2&pid=1-s2.0-S2949704323000045-main.pdf3 a<p>The global pandemic caused by the coronavirus disease 2019 not only exposed the<br />
fragility of global preparedness and response to public health emergence, but also<br />
illustrated the fragmentation and gaps of research and development ecosystem. This<br />
emphasizes the need for planned actions against the potentiality of new pandemics<br />
and requires research to better understand how viruses bridge the animal/human<br />
divide making human-to-human transmission of new diseases possible. Major<br />
challenges to response to new epidemics under the current health framework reside in<br />
the so called 4-CC approach that focuses on Concept, Communication, Coherence,<br />
and Continuity. There is a need to also add a One Health perspective with emphasis<br />
on governance, surveillance, capacity building and multi-disciplinary research to<br />
achieve a holistic and better integrated system. Using a regulatory framework to equip<br />
professionals might facilitate the function of a multi-sector approach that recognizes<br />
the value of their mandates and a One Health approach in their work. Collaborative,<br />
multisectoral actions under the global regulations and guidance would make<br />
evidence-based One Health approaches sustainable and accessible to everyone.</p>
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