01784nas a2200265   4500000000100000008004100001260001600042653002200058653001500080653003300095653003100128100001300159700001800172700001300190700001100203700001600214700001000230700001300240700001200253245007500265300001200340490001200352520114000364022001401504       2023                            d  bElsevier BV10aMolecular Biology10aBiophysics10asmartphone-based diagnostics10adisease biosensing devices1 aPawar AA1 aPatwardhan SB1 aBarage S1 aRaut R1 aLakkakula J1 aRoy A1 aSharma R1 aAnand J00aSmartphone-based diagnostics for biosensing infectious human pathogens  a120-1300 v180-1813 a<p>The widespread usage of smartphones has made accessing vast troves of data easier for everyone. Smartphones are powerful, handy, and easy to operate, making them a valuable tool for improving public health through diagnostics. When combined with other devices and sensors, smartphones have shown potential for detecting, visualizing, collecting, and transferring data, enabling rapid disease diagnosis. In resource-limited settings, the user-friendly operating system of smartphones allows them to function as a point-of-care platform for healthcare and disease diagnosis. Herein, we critically reviewed the smartphone-based biosensors for the diagnosis and detection of diseases caused by infectious human pathogens, such as deadly viruses, bacteria, and fungi. These biosensors use several analytical sensing methods, including microscopic imaging, instrumental interface, colorimetric, fluorescence, and electrochemical biosensors. We have discussed the diverse diagnosis strategies and analytical performances of smartphone-based detection systems in identifying infectious human pathogens, along with future perspectives.</p>
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