02438nas a2200265   4500000000100000008004100001260001600042653002400058653002800082653002700110653004800137653001500185653001000200100001200210700001500222700001600237700001600253700001400269245010800283856015300391300001100544490000700555520159600562022001402158       2023                            d  bElsevier BV10aInfectious Diseases10aCutaneous larva migrans10aSkin diseases Zoonoses10aIntegrated surveillance and Response system10aOne Health10aSudan1 aAhmed A1 aHemaida MA1 aHagelnur AA1 aEltigani HF1 aSiddig EE00aSudden emergence and spread of cutaneous larva migrans in Sudan: A case series calls for urgent actions  uhttps://www.sciencedirect.com/science/article/pii/S2214250923001130/pdfft?md5=ae3873f12b2db3728e581b71e9500880&pid=1-s2.0-S2214250923001130-main.pdf  ae017890 v323 a<p>Cutaneous larva migrans&nbsp;(CLM) is a self-limiting&nbsp;dermatosis&nbsp;parasitic disease&nbsp;that is caused by&nbsp;zoonotic&nbsp;hookworm mainly infects cats, dogs, and accidentally humans. The disease affects hosts through the invasion and the migration of the hookworm larva into top layers of the skin. The disease occurs in tropical and subtropical regions; where people commonly are infected when sitting or barefoot walking on places contaminated with feces of infected cats or dogs. Due to self-limiting nature of the disease, the exact burden and prevalence are commonly underestimated. In this communication, we investigated all cases presented to the skin-diseases outpatient clinic’ at the reference hospital of Tropical Diseases Medicine in Khartoum state between January 2019 and January 2021. This is the first-ever a case series report of cutaneous larva migrans in Sudan. We identified 15 cases of CLM presented with rash (100 %), redness of skin (67 %), and only adults were presented with larva crawling under their skins (27 %). Infection sites were (53 %) leg, (40 %) foot, only 7 % showed&nbsp;abdominal infection. The majority of patients were children or young adults, 47 % of them are ≤5 year-old, male to female ratio is 2.75:1. Duration of infection was one to three weeks and all patients fully recovered after treatment with&nbsp;albendazole. This urges for One Health interventions including&nbsp;deworming&nbsp;cats and dogs, improving water, sanitation, and hygiene, community-engagement and raising awareness in area with risk of infection.</p>
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