01148nas a2200253   4500000000100000008004100001260002300042653002700065653001700092653001500109653003900124653001300163653001400176653002600190100001600216700001400232700002100246245007500267856007200342300000900414490000700423520045000430022001400880       2023                            d  bFrontiers Media SA10aPharmacology (medical)10aPharmacology10aeumycetoma10aNeglected tropical diseases (NTDs)10amycology10aSkin NTDs10aMadurella mycetomatis1 aChandler DJ1 aBonifaz A1 avan de Sande WWJ00aAn update on the development of novel antifungal agents for eumycetoma  uhttps://www.frontiersin.org/articles/10.3389/fphar.2023.1165273/pdf  a1-110 v143 a<p>Eumycetoma, a chronic subcutaneous mycosis, responds poorly to the available antifungal treatments and patients often require extensive surgical resection or amputation of the affected limb. More effective treatments are needed for eumycetoma. This article will describe some of the approaches being used to develop and evaluate new treatments for eumycetoma, summarise the latest developments and discuss the challenges that lie ahead.</p>
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