01476nas a2200193   4500000000100000008004100001260001000042653002900052653001500081100001700096700001700113700001600130700002300146700001700169245006400186300001200250520100200262020001801264       2023                            d  bWiley10aAntimicrobial resistance10aOne Health1 aGunasekara Y1 aKottawatta S1 aNisansala T1 aSilva‐Fletcher A1 aKalupahana R00aTackling Antimicrobial Resistance Needs One Health Approach  a309-3233 a<p>Antimicrobial resistance (AMR) is an increasingly pervasive issue worldwide, with increasing morbidity and mortality rates in both humans and animals. Bacteria are not limited to one species, and the majority of emerging human infections originate from animals. Both human and animal sectors use the same antimicrobials, leading to residue accumulation in the environment. Therefore, AMR in one sector has the potential to extend to other sectors, with the environment and wild animals acting as a reservoir for resistance. Humans can be exposed to animal-originated AMR through animal-based food products and contaminated water, while animals face exposure to AMR present in humans through environmental contamination. Hence, addressing the health threats posed by AMR at the intersection of people, animals, and their environments is a timely need. Since the One Health concept is based on a transdisciplinary approach, it is important to tackle this global health issue systematically.</p>
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