01861nas a2200337 4500000000100000008004100001260001200042653002400054653005700078653004000135653001900175653001000194653002200204653001500226653001500241100002600256700002500282700002300307700002600330700002300356700002300379700002000402700002400422700002000446245008200466856006600548300000900614490000600623520088000629022001401509 2023 d bMDPI AG10aInfectious Diseases10aPublic Health, Environmental and Occupational Health10aGeneral Immunology and Microbiology10aChagas disease10aGuide10aTrypanosoma cruzi10atriatomine10areservoirs1 aDe Fuentes-Vicente JA1 aSantos-Hernández NG1 aRuiz-Castillejos C1 aEspinoza-Medinilla EE1 aFlores-Villegas AL1 ade Alba-Alvarado M1 aCabrera-Bravo M1 aMoreno-Rodríguez A1 aVidal-López DG00aWhat Do You Need to Know before Studying Chagas Disease? A Beginner’s Guide uhttps://www.mdpi.com/2414-6366/8/7/360/pdf?version=1688976802 a1-190 v83 a

Chagas disease is one of the most important tropical infections in the world and mainly affects poor people. The causative agent is the hemoflagellate protozoan Trypanosoma cruzi, which circulates among insect vectors and mammals throughout the Americas. A large body of research on Chagas disease has shown the complexity of this zoonosis, and controlling it remains a challenge for public health systems. Although knowledge of Chagas disease has advanced greatly, there are still many gaps, and it is necessary to continue generating basic and applied research to create more effective control strategies. The aim of this review is to provide up-to-date information on the components of Chagas disease and highlight current trends in research. We hope that this review will be a starting point for beginners and facilitate the search for more specific information.

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