02158nas a2200325 4500000000100000008004100001260001200042653001300054653002700067653001700094653001000111653001900121653001200140653001200152653001500164653001100179653001400190100002200204700002500226700002000251700001900271700001300290700001600303245008600319856006800405300000900473490000700482520132900489022001401818 2023 d bMDPI AG10aVirology10aMicrobiology (medical)10aMicrobiology10aGabon10aonchocerciasis10acontrol10aprogram10aprevalence10avector10areservoir1 aEyang-Assengone E1 aMakouloutou-Nzassi P1 aMbou-Boutambe C1 aBangueboussa F1 aAtsame J1 aBoundenga L00aStatus of Onchocerciasis Elimination in Gabon and Challenges: A Systematic Review uhttps://www.mdpi.com/2076-2607/11/8/1946/pdf?version=1690634608 a1-110 v113 a

Control and treatment programs (CDTI) have been set up nationally in all endemic countries to overcome the impact of onchocerciasis on the affected populations. However, Gabon must still succeed in setting up real onchocerciasis control programs. Here, various database articles have been used to provide the scientific community with a summary document showing the mapping of this disease in Gabon. The articles dealing with onchocerciasis, animal reservoirs, surveillance, and elimination were analyzed. Results showed that little research has been performed. Most studies are concentrated in one region (The area of Lastourville). In addition, we observed that the distribution of the disease varies significantly across the country. Indeed, specific environments present a hyper-endemicity of the disease, while others are meso and hypo-endemic. So, we found some departments with a prevalence ranging from 0% to over 20%; within them, villages had infection levels comprising 10% to 60%, indicating potential hotspots. Vectors activities were studied in some areas. This paper showed the challenges encountered in the country to eliminate this disease. One solution is a deeper understanding of the disease’s bioecology to establish effective health policies to eliminate onchocerciasis in Gabon effectively.

 a2076-2607