02892nas a2200289   4500000000100000008004100001260003300042653001300075653001500088653001800103653002900121653003600150100001700186700001300203700001500216700001500231700001500246700001400261700001300275700001200288700001400300245010400314250000800418856026000426300001200686520190400698       2024                            d  bUnique Scientific Publishers10aZoonosis10aOne Health10aPublic Health10aVeterinary Public Health10aInterdisciplinary collaboration1 aMukhtar M. U1 aFayyaz Z1 aAftab M. M1 aNawaz M. H1 aJaved M. A1 aHussain B1 aShahid R1 aUllah F1 aBadshah F00aOne Health Approach to Zoonosis: Integrating Medicine, Veterinary science and Environmental Science  a1st  uhttps://www.researchgate.net/profile/Farhad-Badshah-4/publication/377117156_One_Health_Approach_to_Zoonosis_Integrating_Medicine_Veterinary_science_and_Environmental_Science/links/659682df6f6e450f19c92f88/One-Health-Approach-to-Zoonosis-Integrating-Medici  a226-2363 a<p>Zoonotic diseases that transmit from animals to humans pose a major global health threat, accounting for over 60% of infectious diseases. Tackling these complex "one health" challenges requires integrating human medicine, veterinary science, and environmental monitoring into a unified framework. This chapter of the book provides a comprehensive overview of the One Health approach for addressing zoonosis. Tracing foundational concepts from Hippocrates through seminal thinkers like Virchow and James Steele, it chronicles paradigm shifts recognizing interdependencies between human, animal, and environmental health. Detailed case examples illustrate effective applications of One Health principles, from curbing sleeping sickness in Uganda by linking human outbreaks with animal reservoirs and vector control, to mitigating Rift Valley Fever in Kenya through joint animal-human health response systems. Core One Health focus areas for zoonosis include strengthened surveillance coordinating human and animal data streams to detect outbreaks early, comparative research on disease transmission pathways across species, and collaborative policies supporting prevention and control programs. The chapter emphasizes that overcoming systemic barriers limiting cross-sectoral coordination is essential to managing these complex risks, requiring medical experts, veterinary professionals, and environmental scientists to align efforts within an interconnected framework. Key recommendations include fostering interdisciplinary cooperation, establishing regular communication platforms, addressing resource constraints limiting One Health infrastructure, and actively engaging local communities. Ultimately, this holistic approach creates a shared defence against endemic and emergent zoonosis by enhancing preparedness, resilience, and risk reduction at the human-animal-environment interface.</p>