TY - JOUR
KW - atypical cutaneous leishmaniasis
KW - Leishmania donovani
KW - Western Ghats
AU - Fathima PA
AU - Shah HK
AU - Aiswarya RS
AU - Ajithlal PM
AU - Shailaja TV
AU - Shubin C
AU - Reena KJ
AU - Saini P
AB - <p><strong>Background:</strong> Different clinical manifestations of leishmaniasis (cutaneous and visceral) caused by Leishmania donovani have been reported from Kerala, India. Leishmania donovani causing cutaneous leishmaniasis (CL) (also called atypical CL [ACL]) is one of the major health concerns in the Western Ghats belt of the state.</p>

<p><strong>Methods:</strong> Skin biopsies of 20 patients with suspected CL from Nilambur, Kerala, were processed for CL diagnosis during the period 2022–2023. Parasite species were characterized using Leishmania-specific Internal Transcribed Spacer-Ⅰ (ITS-Ⅰ) PCR and ITS-Ⅰ RFLP analysis.</p>

<p><strong>Result: </strong>A total of 18 cases were confirmed to be CL and the parasite was identified as L. donovani.</p>

<p><strong>Conclusion:</strong> These indigenous ACL (CL due to L. donovani) reports from the small foci of Nilambur reveal an emerging endemic zone of leishmaniasis in the Western Ghats.</p>

BT - Transactions of The Royal Society of Tropical Medicine and Hygiene
DO - 10.1093/trstmh/trae102
LA - ENG
M3 - Article
N2 - <p><strong>Background:</strong> Different clinical manifestations of leishmaniasis (cutaneous and visceral) caused by Leishmania donovani have been reported from Kerala, India. Leishmania donovani causing cutaneous leishmaniasis (CL) (also called atypical CL [ACL]) is one of the major health concerns in the Western Ghats belt of the state.</p>

<p><strong>Methods:</strong> Skin biopsies of 20 patients with suspected CL from Nilambur, Kerala, were processed for CL diagnosis during the period 2022–2023. Parasite species were characterized using Leishmania-specific Internal Transcribed Spacer-Ⅰ (ITS-Ⅰ) PCR and ITS-Ⅰ RFLP analysis.</p>

<p><strong>Result: </strong>A total of 18 cases were confirmed to be CL and the parasite was identified as L. donovani.</p>

<p><strong>Conclusion:</strong> These indigenous ACL (CL due to L. donovani) reports from the small foci of Nilambur reveal an emerging endemic zone of leishmaniasis in the Western Ghats.</p>

PB - Oxford University Press (OUP)
PY - 2024
T2 - Transactions of The Royal Society of Tropical Medicine and Hygiene
TI - Cutaneous leishmaniasis: a neglected clinical manifestation among the tribal population in Nilambur, Kerala, India
SN - 0035-9203, 1878-3503
ER -