TY - JOUR
KW - Quality of Life
KW - HIV co-infection
KW - Visceral leishmaniasis (VL)
KW - WHOQOL-BREF
AU - Pund R
AU - Vishwas G
AU - Madhukar M
AU - Pandey K
AU - Dhingra S
AB - <p><strong>Background</strong> This study was aimed to evaluates the quality of life using WHOQOL-BREF in VL patients co-infected with HIV in Bihar, India.</p>

<p><strong>Methods</strong> This cross-sectional study enrolled 240 participants: 60 HIV-VL co-infected, 60 HIV, 60 VL and 60 healthy individuals. Socio-demographic data and QOL assessments used the Hindi WHOQOL-BREF questionnaire. The data were compared using the chi-square test, One-Way ANOVA followed by Tukey’s post-hoc Test. Generalised linear regression was performed for analyses of predictors of QOL, as well as the socio-economic status was determined by using the Modifed Kuppuswamy socio-economic Scale 2022.</p>

<p><strong>Results</strong> HIV-VL co-infected patients reported signifcantly lower QOL scores across all domains (physical, psychological, social relationships, and environmental) compared to healthy individuals (p &lt; 0.05). Notably, psychological (12.17±1.17), social relationship (5.90±1.16), and environmental (14.10±1.68) domains were severely impacted in HIV-VL coinfection in contrast to HIV (p&lt;0.05) and VL (p&lt;0.05).</p>

<p><strong>Conclusion</strong> HIV-VL co-infection profoundly afects quality of life, emphasizing the need for targeted interventions addressing psychological, social and environmental well-being. Future research should prioritize strategies improving QOL and assessing long-term treatment efects in HIV-VL co-infection</p>

BT - Journal of Health, Population and Nutrition
DO - 10.1186/s41043-025-00821-6
IS - 1
LA - eng
M3 - Research Article
N2 - <p><strong>Background</strong> This study was aimed to evaluates the quality of life using WHOQOL-BREF in VL patients co-infected with HIV in Bihar, India.</p>

<p><strong>Methods</strong> This cross-sectional study enrolled 240 participants: 60 HIV-VL co-infected, 60 HIV, 60 VL and 60 healthy individuals. Socio-demographic data and QOL assessments used the Hindi WHOQOL-BREF questionnaire. The data were compared using the chi-square test, One-Way ANOVA followed by Tukey’s post-hoc Test. Generalised linear regression was performed for analyses of predictors of QOL, as well as the socio-economic status was determined by using the Modifed Kuppuswamy socio-economic Scale 2022.</p>

<p><strong>Results</strong> HIV-VL co-infected patients reported signifcantly lower QOL scores across all domains (physical, psychological, social relationships, and environmental) compared to healthy individuals (p &lt; 0.05). Notably, psychological (12.17±1.17), social relationship (5.90±1.16), and environmental (14.10±1.68) domains were severely impacted in HIV-VL coinfection in contrast to HIV (p&lt;0.05) and VL (p&lt;0.05).</p>

<p><strong>Conclusion</strong> HIV-VL co-infection profoundly afects quality of life, emphasizing the need for targeted interventions addressing psychological, social and environmental well-being. Future research should prioritize strategies improving QOL and assessing long-term treatment efects in HIV-VL co-infection</p>

PB - Springer Science and Business Media LLC
PY - 2025
EP - 11
T2 - Journal of Health, Population and Nutrition
TI - Assessment of quality of life in visceral leishmaniasis patients coinfected with HIV: a comparative study in Bihar, India
UR - https://link.springer.com/article/10.1186/s41043-025-00821-6
VL - 44
SN - 2072-1315
ER -