Leishmaniasis is a significant neglected tropical disease (NTD) with profound public health and socioeconomic impacts across North Africa. This review provides an emphasis on the epidemiology, transmission dynamics, and diagnostic evolution of the disease.
Ecological diversity, rapid urbanization, climate change, and population displacement have reshaped transmission cycles. Cutaneous Leishmaniasis (CL) remains hyper-endemic in North Africa, while Visceral Leishmaniasis (VL) continues to cause high mortality in East Africa. Emerging molecular tools are being evaluated against current diagnostic gold standards, highlighting systemic gaps in surveillance and treatment accessibility.
This work provides essential insights on epidemiology, transmission, and diagnosis of Leishmaniasis in Egypt and other North African countries highlighting the impact of ecological and demographic factors on disease dynamics and identifying gaps in surveillance and treatment.
BT - Current Tropical Medicine Reports DA - 06/2026 DO - 10.1007/s40475-026-00371-9 IS - 1 LA - ENG M3 - Article N2 -Leishmaniasis is a significant neglected tropical disease (NTD) with profound public health and socioeconomic impacts across North Africa. This review provides an emphasis on the epidemiology, transmission dynamics, and diagnostic evolution of the disease.
Ecological diversity, rapid urbanization, climate change, and population displacement have reshaped transmission cycles. Cutaneous Leishmaniasis (CL) remains hyper-endemic in North Africa, while Visceral Leishmaniasis (VL) continues to cause high mortality in East Africa. Emerging molecular tools are being evaluated against current diagnostic gold standards, highlighting systemic gaps in surveillance and treatment accessibility.
This work provides essential insights on epidemiology, transmission, and diagnosis of Leishmaniasis in Egypt and other North African countries highlighting the impact of ecological and demographic factors on disease dynamics and identifying gaps in surveillance and treatment.
PB - Springer Science and Business Media LLC PY - 2026 T2 - Current Tropical Medicine Reports TI - Leishmaniasis in North Africa; Ecological Dynamics and Control Challenges VL - 13 SN - 2196-3045 ER -