Objective:
To study assessed factors associated with mass drug administration (MDA) noncompliance for lymphatic filariasis in urban and rural Indonesian communities.
Methods:
A cross-sectional analysis was conducted using a subset of nationally representative data from the 2023 Indonesian Health Survey (Survei Kesehatan Indonesia, SKI). Participants were classified as residing in urban ( n =469 549) and rural ( n =407 982) and interviewed regarding anti-filarial drugs intake over the past 5 years. Logistic regression models were constructed to identify factors associated with MDA noncompliance.
Results:
A total of 877 531 individuals from 284 177 households across 514 districts in 38 provinces were included in the study. Among them, 136 526 (15.56%) took anti-filarial drugs in five years; of these, 27 113 (19.86%) never complied fully, revealing significant urban-rural disparities. In urban areas, noncompliance with MDA was associated with pre-working age group (a OR 1.58; 95% CI 1.21-2.07) and those with self-reported LF (a OR 1.47; 95% CI 1.13-1.91). Awareness of health facilities was protective against noncompliance (a OR 0.29; 95% CI 0.11-0.77). In contrast, rural noncompliance was associated with transportation cost barriers (a OR 1.55; 95% CI 1.21-1.99), children aged 2-5 years (a OR 1.43; 95% CI 1.08-1.87), mobile phone ownership (a OR 1.40; 95% CI 1.12-1.75), and self-reported LF (a OR 1.47; 95% CI 1.19-1.82).
Conclusions:
Distinct demographic, socioeconomic, and accessibility factors influence MDA noncompliance in Indonesia. Targeted behavioral interventions in urban areas and improved communication and access in rural regions are essential for LF elimination.
BT - Asian Pacific Journal of Tropical Medicine DA - 08/2026 DO - 10.4103/apjtm.apjtm_93_26 IS - 8 LA - ENG M3 - Article N2 -Objective:
To study assessed factors associated with mass drug administration (MDA) noncompliance for lymphatic filariasis in urban and rural Indonesian communities.
Methods:
A cross-sectional analysis was conducted using a subset of nationally representative data from the 2023 Indonesian Health Survey (Survei Kesehatan Indonesia, SKI). Participants were classified as residing in urban ( n =469 549) and rural ( n =407 982) and interviewed regarding anti-filarial drugs intake over the past 5 years. Logistic regression models were constructed to identify factors associated with MDA noncompliance.
Results:
A total of 877 531 individuals from 284 177 households across 514 districts in 38 provinces were included in the study. Among them, 136 526 (15.56%) took anti-filarial drugs in five years; of these, 27 113 (19.86%) never complied fully, revealing significant urban-rural disparities. In urban areas, noncompliance with MDA was associated with pre-working age group (a OR 1.58; 95% CI 1.21-2.07) and those with self-reported LF (a OR 1.47; 95% CI 1.13-1.91). Awareness of health facilities was protective against noncompliance (a OR 0.29; 95% CI 0.11-0.77). In contrast, rural noncompliance was associated with transportation cost barriers (a OR 1.55; 95% CI 1.21-1.99), children aged 2-5 years (a OR 1.43; 95% CI 1.08-1.87), mobile phone ownership (a OR 1.40; 95% CI 1.12-1.75), and self-reported LF (a OR 1.47; 95% CI 1.19-1.82).
Conclusions:
Distinct demographic, socioeconomic, and accessibility factors influence MDA noncompliance in Indonesia. Targeted behavioral interventions in urban areas and improved communication and access in rural regions are essential for LF elimination.
PB - Ovid Technologies (Wolters Kluwer Health) PY - 2026 SP - 354 EP - 366 T2 - Asian Pacific Journal of Tropical Medicine TI - Assessing factors influencing noncompliance with mass drug administration for lymphatic filariasis in urban and rural Indonesia UR - https://www.ovid.com/jnls/aptm/pdf/10.4103/apjtm.apjtm_93_26~assessing-factors-influencing-noncompliance-with-mass-drug VL - 19 SN - 1995-7645, 2352-4146 ER -