TY - JOUR AU - Lönnroth K AU - Migliori GB AU - Abubakar I AU - D'Ambrosio L AU - Vries G AU - Diel R AU - Douglas P AU - Falzon D AU - Gaudreau M AU - Goletti D AU - González Ochoa E AU - LoBue P AU - Matteelli A AU - Njoo H AU - Solovic I AU - Story A AU - Tayeb T AU - Werf MJ AU - Weil D AU - Zellweger J AU - Abdel Aziz M AU - Al Lawati M AU - Aliberti S AU - Arrazola de Oñate W AU - Barreira D AU - Bhatia V AU - Blasi F AU - Bloom A AU - Bruchfeld J AU - Castelli F AU - Centis R AU - Chemtob D AU - Cirillo DM AU - Colorado A AU - Dadu A AU - Dahle UR AU - De Paoli L AU - Dias H AU - Duarte R AU - Fattorini L AU - Gaga M AU - Getahun H AU - Glaziou P AU - Goguadze L AU - Del Granado M AU - Haas W AU - Järvinen A AU - Kwon G AU - Mosca D AU - Nahid P AU - Nishikiori N AU - Noguer I AU - O'Donnell J AU - Pace-Asciak A AU - Pompa MG AU - Popescu G AU - Robalo Cordeiro C AU - Rønning K AU - Ruhwald M AU - Sculier J AU - Simunović A AU - Smith-Palmer A AU - Sotgiu G AU - Sulis G AU - A Torres-Duque C AU - Umeki K AU - Uplekar M AU - Weezenbeek C AU - Vasankari T AU - Vitillo RJ AU - Voniatis C AU - Wanlin M AU - Raviglione M AB -

This paper describes an action framework for countries with low tuberculosis (TB) incidence (<100 TB cases per million population) that are striving for TB elimination. The framework sets out priority interventions required for these countries to progress first towards "pre-elimination" (<10 cases per million) and eventually the elimination of TB as a public health problem (less than one case per million). TB epidemiology in most low-incidence countries is characterised by a low rate of transmission in the general population, occasional outbreaks, a majority of TB cases generated from progression of latent TB infection (LTBI) rather than local transmission, concentration to certain vulnerable and hard-to-reach risk groups, and challenges posed by cross-border migration. Common health system challenges are that political commitment, funding, clinical expertise and general awareness of TB diminishes as TB incidence falls. The framework presents a tailored response to these challenges, grouped into eight priority action areas: 1) ensure political commitment, funding and stewardship for planning and essential services; 2) address the most vulnerable and hard-to-reach groups; 3) address special needs of migrants and cross-border issues; 4) undertake screening for active TB and LTBI in TB contacts and selected high-risk groups, and provide appropriate treatment; 5) optimise the prevention and care of drug-resistant TB; 6) ensure continued surveillance, programme monitoring and evaluation and case-based data management; 7) invest in research and new tools; and 8) support global TB prevention, care and control. The overall approach needs to be multisectorial, focusing on equitable access to high-quality diagnosis and care, and on addressing the social determinants of TB. Because of increasing globalisation and population mobility, the response needs to have both national and global dimensions.

BT - The European respiratory journal C1 -

http://www.ncbi.nlm.nih.gov/pubmed/25792630?dopt=Abstract

DO - 10.1183/09031936.00214014 J2 - Eur. Respir. J. LA - eng N2 -

This paper describes an action framework for countries with low tuberculosis (TB) incidence (<100 TB cases per million population) that are striving for TB elimination. The framework sets out priority interventions required for these countries to progress first towards "pre-elimination" (<10 cases per million) and eventually the elimination of TB as a public health problem (less than one case per million). TB epidemiology in most low-incidence countries is characterised by a low rate of transmission in the general population, occasional outbreaks, a majority of TB cases generated from progression of latent TB infection (LTBI) rather than local transmission, concentration to certain vulnerable and hard-to-reach risk groups, and challenges posed by cross-border migration. Common health system challenges are that political commitment, funding, clinical expertise and general awareness of TB diminishes as TB incidence falls. The framework presents a tailored response to these challenges, grouped into eight priority action areas: 1) ensure political commitment, funding and stewardship for planning and essential services; 2) address the most vulnerable and hard-to-reach groups; 3) address special needs of migrants and cross-border issues; 4) undertake screening for active TB and LTBI in TB contacts and selected high-risk groups, and provide appropriate treatment; 5) optimise the prevention and care of drug-resistant TB; 6) ensure continued surveillance, programme monitoring and evaluation and case-based data management; 7) invest in research and new tools; and 8) support global TB prevention, care and control. The overall approach needs to be multisectorial, focusing on equitable access to high-quality diagnosis and care, and on addressing the social determinants of TB. Because of increasing globalisation and population mobility, the response needs to have both national and global dimensions.

PY - 2015 T2 - The European respiratory journal TI - Towards tuberculosis elimination: an action framework for low-incidence countries. UR - http://erj.ersjournals.com/content/early/2015/03/18/09031936.00214014.full.pdf+html SN - 1399-3003 ER -