There is a compelling scarcity of pharmaceutical agents for efficacious, safe, and affordable treatment of neglected infectious or tropical diseases such as malaria, trypanosomiasis, leishmaniasis, dengue, lymphatic filariasis, and soil-transmitted helminths, despite their high prevalence in the developing world. Toxicity of drugs, microbial resistance patterns, and long courses of treatments are among the current challenges in effective management of neglected diseases.
BT - PLoS neglected tropical diseases C1 -http://www.ncbi.nlm.nih.gov/pubmed/21980540?dopt=Abstract
DO - 10.1371/journal.pntd.0001221 IS - 9 J2 - PLoS Negl Trop Dis LA - eng M3 - Viewpoint N2 -There is a compelling scarcity of pharmaceutical agents for efficacious, safe, and affordable treatment of neglected infectious or tropical diseases such as malaria, trypanosomiasis, leishmaniasis, dengue, lymphatic filariasis, and soil-transmitted helminths, despite their high prevalence in the developing world. Toxicity of drugs, microbial resistance patterns, and long courses of treatments are among the current challenges in effective management of neglected diseases.
PY - 2011 EP - e1221 T2 - PLoS neglected tropical diseases TI - Innovative partnerships for drug discovery against neglected diseases. UR - http://journals.plos.org/plosntds/article/asset?id=10.1371%2Fjournal.pntd.0001221.PDF VL - 5 SN - 1935-2735 ER -