TY - JOUR KW - Africa KW - Elimination KW - Lymphatic filariasis KW - onchocerciasis KW - Loiasis KW - Neglected tropical diseases (NTDs) AU - Kelly-Hope L AU - Blundell HJ AU - Macfarlane CL AU - Molyneux DH AB -

Lymphatic filariasis (LF) and onchocerciasis are two neglected tropical diseases (NTDs) of public health significance targeted for global elimination. The World Health Organization (WHO) African Region is a priority region, with the highest collective burden of LF and onchocerciasis globally. Coendemic loiasis further complicates elimination due to the risk of adverse events associated with ivermectin treatment. A public health framework focusing on health-related data, systematic collection of data, and analysis and interpretation of data is used to highlight the range of innovative surveillance strategies required for filariasis elimination. The most recent and significant developments include: rapid point-of-care test (POCT) diagnostics; clinical assessment tools; new WHO guidelines; open-access online data portals; mHealth platforms; large-scale prevalence maps; and the optimisation of mathematical models.

BT - Trends in parasitology C1 -

http://www.ncbi.nlm.nih.gov/pubmed/29958813?dopt=Abstract

DO - 10.1016/j.pt.2018.05.004 J2 - Trends Parasitol. LA - eng N2 -

Lymphatic filariasis (LF) and onchocerciasis are two neglected tropical diseases (NTDs) of public health significance targeted for global elimination. The World Health Organization (WHO) African Region is a priority region, with the highest collective burden of LF and onchocerciasis globally. Coendemic loiasis further complicates elimination due to the risk of adverse events associated with ivermectin treatment. A public health framework focusing on health-related data, systematic collection of data, and analysis and interpretation of data is used to highlight the range of innovative surveillance strategies required for filariasis elimination. The most recent and significant developments include: rapid point-of-care test (POCT) diagnostics; clinical assessment tools; new WHO guidelines; open-access online data portals; mHealth platforms; large-scale prevalence maps; and the optimisation of mathematical models.

PY - 2018 T2 - Trends in parasitology TI - Innovative surveillance strategies to support the elimination of filariasis in Africa. SN - 1471-5007 ER -