TY - JOUR KW - Loa loa KW - Microfilariae KW - Monitoring and evaluation KW - onchocerciasis AU - Nana-Djeunga HC AU - Fossuo-Thotchum F AU - Pion S AU - Chesnais C AU - Kubofcik J AU - Mackenzie C AU - Klion A AU - Boussinesq M AU - Nutman T AU - Kamgno J AB -

The specificity of skin snips for onchocerciasis diagnosis is considered to be almost 100%. In this study, molecular methods revealed that microfilariae emerging from skin snips collected from highly microfilaremic Loa loa-infected individuals were largely misidentified as Onchocerca volvulus. This has important implications for onchocerciasis diagnostic testing in Loa-endemic areas.

BT - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America C1 -

http://www.ncbi.nlm.nih.gov/pubmed/30861060?dopt=Abstract

DO - 10.1093/cid/ciz172 J2 - Clin. Infect. Dis. LA - eng N2 -

The specificity of skin snips for onchocerciasis diagnosis is considered to be almost 100%. In this study, molecular methods revealed that microfilariae emerging from skin snips collected from highly microfilaremic Loa loa-infected individuals were largely misidentified as Onchocerca volvulus. This has important implications for onchocerciasis diagnostic testing in Loa-endemic areas.

PY - 2019 T2 - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America TI - Loa loa microfilariae in skin snips: consequences for onchocerciasis monitoring and evaluation in L. loa endemic areas. SN - 1537-6591 ER -