In the early 20th century, a series of epidemics across equatorial Africa brought African sleeping sickness (human African trypanosomiasis, HAT) to the attention of the European colonial administrations. This disease presented an exciting challenge for microbiologists across Europe to study the disease, discover the pathogen and search for an effective treatment. In 1923, the first "remedy for tropical diseases"-Suramin-manufactured by Bayer AG came onto the market under the brand name "Germanin." The development and life cycle of this product-which today is still the medicine of choice for Trypanosoma brucei (T.b), hodesiense infections-reflect medical progress as well as the successes and failures in fighting the disease in the context of historic political changes over the last 100 years.
BT - Tropical medicine and infectious disease C1 - https://www.ncbi.nlm.nih.gov/pubmed/32164154 DA - 03/2020 DO - 10.3390/tropicalmed5010042 IS - 1 J2 - Trop Med Infect Dis LA - eng N2 -In the early 20th century, a series of epidemics across equatorial Africa brought African sleeping sickness (human African trypanosomiasis, HAT) to the attention of the European colonial administrations. This disease presented an exciting challenge for microbiologists across Europe to study the disease, discover the pathogen and search for an effective treatment. In 1923, the first "remedy for tropical diseases"-Suramin-manufactured by Bayer AG came onto the market under the brand name "Germanin." The development and life cycle of this product-which today is still the medicine of choice for Trypanosoma brucei (T.b), hodesiense infections-reflect medical progress as well as the successes and failures in fighting the disease in the context of historic political changes over the last 100 years.
PY - 2020 T2 - Tropical medicine and infectious disease TI - From Colonial Research Spirit to Global Commitment: Bayer and African Sleeping Sickness in the Mirror of History. UR - https://www.researchgate.net/publication/339836136_From_Colonial_Research_Spirit_to_Global_Commitment_Bayer_and_African_Sleeping_Sickness_in_the_Mirror_of_History VL - 5 SN - 2414-6366 ER -