TY - JOUR
KW - Public Health, Environmental and Occupational Health
KW - Health(social science)
KW - General Medicine
KW - Ivermectin
AU - Weil G
AU - Jacobson JA
AU - King J
AB - <jats:title>Abstract</jats:title>
               <jats:p>The Global Programme to Eliminate Lymphatic Filariasis (LF) is using mass drug administration (MDA) of antifilarial medications to treat filarial infections, prevent disease and interrupt transmission. Almost 500 million people receive these medications each year. Clinical trials have recently shown that a single dose of a triple-drug combination comprised of ivermectin, diethylcarbamazine and albendazole (IDA) is dramatically superior to widely used two-drug combinations for clearing larval filarial parasites from the blood of infected persons. A large multicenter community study showed that IDA was well-tolerated when it was provided as MDA. IDA was rapidly advanced from clinical trial to policy and implementation; it has the potential to accelerate LF elimination in many endemic countries.</jats:p>
BT - International Health
DO - 10.1093/inthealth/ihaa046
IS - Supplement_1
LA - eng
N2 - <jats:title>Abstract</jats:title>
               <jats:p>The Global Programme to Eliminate Lymphatic Filariasis (LF) is using mass drug administration (MDA) of antifilarial medications to treat filarial infections, prevent disease and interrupt transmission. Almost 500 million people receive these medications each year. Clinical trials have recently shown that a single dose of a triple-drug combination comprised of ivermectin, diethylcarbamazine and albendazole (IDA) is dramatically superior to widely used two-drug combinations for clearing larval filarial parasites from the blood of infected persons. A large multicenter community study showed that IDA was well-tolerated when it was provided as MDA. IDA was rapidly advanced from clinical trial to policy and implementation; it has the potential to accelerate LF elimination in many endemic countries.</jats:p>
PB - Oxford University Press (OUP)
PY - 2020
SP - S60
EP - S64
T2 - International Health
TI - A triple-drug treatment regimen to accelerate elimination of lymphatic filariasis: From conception to delivery
UR - https://academic.oup.com/inthealth/article-pdf/13/Supplement_1/S60/35056130/ihaa046.pdf
VL - 13
SN - 1876-3413, 1876-3405
ER -