TY - JOUR
KW - General Medicine
KW - Wound care
AU - Kim KJ
AU - Min JH
AU - Yoo I
AU - Kim SW
AU - Lee J
AU - Ryu S
AU - You YH
AU - Park JS
AU - Jeong WJ
AU - Cho YC
AU - Oh SK
AU - In YN
AU - Ahn HJ
AU - Kang CS
AU - Kyung H
AU - Lee BK
AU - Lee DH
AU - Lee DH
AB - This retrospective cohort study aimed to compare the effectiveness of conventional treatment and ultra-early application of negative pressure wound therapy (NPWT) in patients with snakebites.

Patients who visited the emergency department within 24 hours after a snakebite were assigned to the non- NPWT or NPWT group. Swelling resolution time and rates of necrosis, infection, and operations were compared between the 2 groups. The Stony Brook Scar Evaluation Scale was used to measure short- and long-term wound healing results.

Among the included 61 patients, the swelling resolution time was significantly shorter in the NPWT group than in non- NPWT group (P = .010). The NPWT group showed lower necrosis (4.3% versus 36.8%; P = .003) and infection (13.2% and 4.3%; P = .258) rates than the non- NPWT group. The median Stony Brook Scar Evaluation Scale scores were higher in the NPWT group than in the non- NPWT group (P< .001).

These findings suggest that ultra-early application of NPWT reduces edema, promotes wound healing, and prevents necrosis in patients with snakebites.
BT - Medicine
DO - 10.1097/md.0000000000024290
IS - 3
LA - eng
N2 - This retrospective cohort study aimed to compare the effectiveness of conventional treatment and ultra-early application of negative pressure wound therapy (NPWT) in patients with snakebites.

Patients who visited the emergency department within 24 hours after a snakebite were assigned to the non- NPWT or NPWT group. Swelling resolution time and rates of necrosis, infection, and operations were compared between the 2 groups. The Stony Brook Scar Evaluation Scale was used to measure short- and long-term wound healing results.

Among the included 61 patients, the swelling resolution time was significantly shorter in the NPWT group than in non- NPWT group (P = .010). The NPWT group showed lower necrosis (4.3% versus 36.8%; P = .003) and infection (13.2% and 4.3%; P = .258) rates than the non- NPWT group. The median Stony Brook Scar Evaluation Scale scores were higher in the NPWT group than in the non- NPWT group (P< .001).

These findings suggest that ultra-early application of NPWT reduces edema, promotes wound healing, and prevents necrosis in patients with snakebites.
PB - Ovid Technologies (Wolters Kluwer Health)
PY - 2021
EP - e24290
T2 - Medicine
TI - Negative pressure wound therapy for skin necrosis prevention after snakebite in the emergency department
TT - A retrospective cohort study
UR - https://journals.lww.com/md-journal/Fulltext/2021/01220/Negative_pressure_wound_therapy_for_skin_necrosis.135.aspx
VL - 100
SN - 0025-7974, 1536-5964
ER -