TY - JOUR
KW - Microbiology (medical)
KW - Infectious Diseases
KW - General Medicine
AU - Lim W
AU - Eadie K
AU - Konings M
AU - van de Sande W
AB - Mycetoma, a neglected tropical disease, is a chronic granulomatous subcutaneous infection caused by bacteria(actinomycetoma) and fungi(eumycetoma). MycetOS is an ongoing community-driven, open-source-drug-discovery programme aiming to discover new drugs that can treat eumycetoma. Currently, Itraconazole is the only option available, yet, treatment takes years and 25% of patients have recurrences. Amputation of the affected limbs are common and is a huge socio-economic burden for patients in tropical and sub-saharan countries. There is an urgent need to discover new drugs to treat eumycetoma.
BT - International Journal of Infectious Diseases
DO - 10.1016/j.ijid.2020.09.1018
LA - eng
N2 - Mycetoma, a neglected tropical disease, is a chronic granulomatous subcutaneous infection caused by bacteria(actinomycetoma) and fungi(eumycetoma). MycetOS is an ongoing community-driven, open-source-drug-discovery programme aiming to discover new drugs that can treat eumycetoma. Currently, Itraconazole is the only option available, yet, treatment takes years and 25% of patients have recurrences. Amputation of the affected limbs are common and is a huge socio-economic burden for patients in tropical and sub-saharan countries. There is an urgent need to discover new drugs to treat eumycetoma.
PB - Elsevier BV
PY - 2020
EP - 388
T2 - International Journal of Infectious Diseases
TI - MycetOS – An open research model discover new drugs to treat one of the most neglected disease – Mycetoma
UR - https://www.ijidonline.com/action/showPdf?pii=S1201-9712%2820%2931735-5
VL - 101
SN - 1201-9712
ER -